On 14/01/2017 13:11, Andrew wrote:
On 13/01/2017 11:39, whisky-dave wrote:

exactly he was taking aprin so not to get a stroke as he;d heard that
it thins the blood so yuo;re less
likely to get a a blood clot

No it doesn't thin your blood. Medical myth, commonly propagated
by people who should know better (typically nurses), presumably
because they think the patient is too thick to understand how
they work.

Aspirin interferes with the platelets normal function of
metamorphosing into a sticky plug when it encounters exposed
collagen, as when you cut yourself.This is measured by the
bleeding time of about 2 mins.

Warfarin, Heparin and others act on the blood coagulation
stages, normally triggered off by a cut, which pass
throughseveral factors (like Factor VIII, deficient or
defective in haemophiliacs) and eventually polymerise
fibrin into strands that get enmeshed in the platelet
plug to seal the wound after the platelets have plugged
it.


An interesting discussion. What's the advantage of drugs like
Clopidogrel over Warfarin or Aspirin?

GB wrote:

On 14/01/2017 13:00, Andrew wrote:
On 13/01/2017 11:06, GB wrote:
On 13/01/2017 09:06, Nightjar wrote:
On 12-Jan-17 8:05 PM, Andrew wrote:
...
5 times the cost of ordinary 300 mg aspirin

But still cheap enough.

which can be cut into
four with a sharp knife. ...

I have many years of experience of cutting pills and, if one in the
correct dose size is available, I would always prefer to use that to
cutting down a larger pill. Even with a lot of practice, getting the
dose correct by cutting is never certain.


Boots sell 100 dispersible 75mg aspirin tablets for £1.69. So, the
savings to be made are tiny.



What do you mean by tiny ?.

Well under NMW for the time spent.



16 300 mg aspirins are 30p in Sainsbury. That is 64 days supply
for 30p.

You're actually understating the savings, because Asda sell 300 mg
aspirins for 28p for 16.

Whereas Morrisons sell 100 75mg dispersible aspirin for 99p. At under
3/- a month extra cost I'm certainly not going to be cutting up tablets.


--

Roger Hayter

wrote in message
...
On 14/01/2017 13:11, Andrew wrote:
On 13/01/2017 11:39, whisky-dave wrote:

exactly he was taking aprin so not to get a stroke as he;d heard that
it thins the blood so yuo;re less
likely to get a a blood clot

No it doesn't thin your blood. Medical myth, commonly propagated
by people who should know better (typically nurses), presumably
because they think the patient is too thick to understand how
they work.

Aspirin interferes with the platelets normal function of
metamorphosing into a sticky plug when it encounters exposed
collagen, as when you cut yourself.This is measured by the
bleeding time of about 2 mins.

Warfarin, Heparin and others act on the blood coagulation
stages, normally triggered off by a cut, which pass
throughseveral factors (like Factor VIII, deficient or
defective in haemophiliacs) and eventually polymerise
fibrin into strands that get enmeshed in the platelet
plug to seal the wound after the platelets have plugged
it.


An interesting discussion. What's the advantage of drugs like Clopidogrel
over Warfarin or Aspirin?

Better than warfarin in the sense that you dont need repeated
blood test to check that you are getting the correct dose.

Much more effective than low dose aspirin and doesnt
have the stomach effect that aspirin does with some people.
Not currently recommended to be used continually for years
after the heart attack tho and certainly not recommended as
a preventative for those who havent had a heart attack or stroke.

And some stuff in the diet like grapefruit make it ineffective.

On Thu, 12 Jan 2017 13:59:18 +0000, GB wrote:

There are two types of stroke: a) due to blockage, which is the most
common (ischaemic), or b) due to a burst blood vessel (haemorrhagic).
The treatments are the opposite, ie a blood thinner for the clot or a
clotting agent for the burst.

You're basically having to make a choice with a certain amount of pot-
luck here. You could take an aspirin and it might well save your life if
it's a block, but might well kill you if it's a bleed. Question is, what
is your overall health profile like? Which is it most likely to be for
your profile type? And how lucky do you feel today, punk?

"Huge" wrote in message
...
On 2017-01-14, wrote:
On 14/01/2017 13:11, Andrew wrote:
On 13/01/2017 11:39, whisky-dave wrote:

exactly he was taking aprin so not to get a stroke as he;d heard that
it thins the blood so yuo;re less
likely to get a a blood clot

No it doesn't thin your blood. Medical myth, commonly propagated
by people who should know better (typically nurses), presumably
because they think the patient is too thick to understand how
they work.

Aspirin interferes with the platelets normal function of
metamorphosing into a sticky plug when it encounters exposed
collagen, as when you cut yourself.This is measured by the
bleeding time of about 2 mins.

Warfarin, Heparin and others act on the blood coagulation
stages, normally triggered off by a cut, which pass
throughseveral factors (like Factor VIII, deficient or
defective in haemophiliacs) and eventually polymerise
fibrin into strands that get enmeshed in the platelet
plug to seal the wound after the platelets have plugged
it.


An interesting discussion. What's the advantage of drugs like
Clopidogrel over Warfarin or Aspirin?

Clopidogrel's benefit is primarily in those who smoke cigarettes, with
only slight benefit in those who do not.

BULL****. I don’t smoke and that's not what the protocol here says either.

On 15/01/2017 11:20, Huge wrote:
On 2017-01-14, wrote:
On 14/01/2017 13:11, Andrew wrote:
On 13/01/2017 11:39, whisky-dave wrote:

exactly he was taking aprin so not to get a stroke as he;d heard that
it thins the blood so yuo;re less
likely to get a a blood clot

No it doesn't thin your blood. Medical myth, commonly propagated
by people who should know better (typically nurses), presumably
because they think the patient is too thick to understand how
they work.

Aspirin interferes with the platelets normal function of
metamorphosing into a sticky plug when it encounters exposed
collagen, as when you cut yourself.This is measured by the
bleeding time of about 2 mins.

Warfarin, Heparin and others act on the blood coagulation
stages, normally triggered off by a cut, which pass
throughseveral factors (like Factor VIII, deficient or
defective in haemophiliacs) and eventually polymerise
fibrin into strands that get enmeshed in the platelet
plug to seal the wound after the platelets have plugged
it.


An interesting discussion. What's the advantage of drugs like
Clopidogrel over Warfarin or Aspirin?

Clopidogrel's benefit is primarily in those who smoke cigarettes, with
only slight benefit in those who do not.

??

On Sun, 15 Jan 2017 22:42:10 +0000, nospam wrote:

On 15/01/2017 11:20, Huge wrote:
On 2017-01-14, wrote:
On 14/01/2017 13:11, Andrew wrote:
On 13/01/2017 11:39, whisky-dave wrote:

exactly he was taking aprin so not to get a stroke as he;d heard
that it thins the blood so yuo;re less
likely to get a a blood clot

No it doesn't thin your blood. Medical myth, commonly propagated by
people who should know better (typically nurses), presumably because
they think the patient is too thick to understand how they work.

Aspirin interferes with the platelets normal function of
metamorphosing into a sticky plug when it encounters exposed
collagen, as when you cut yourself.This is measured by the bleeding
time of about 2 mins.

Warfarin, Heparin and others act on the blood coagulation stages,
normally triggered off by a cut, which pass throughseveral factors
(like Factor VIII, deficient or defective in haemophiliacs) and
eventually polymerise fibrin into strands that get enmeshed in the
platelet plug to seal the wound after the platelets have plugged it.


An interesting discussion. What's the advantage of drugs like
Clopidogrel over Warfarin or Aspirin?

Clopidogrel's benefit is primarily in those who smoke cigarettes, with
only slight benefit in those who do not.

??

Presumably it treats a particular kind of 'stickiness' mostly produced by
smoking?

It was prescribed for elderly M-I-L years ago, and she hadn't smoked for
about 30 years at the time.



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wish to copy them they can pay me £1 a message.
Use the BIG mirror service in the UK: http://www.mirrorservice.org
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"Bob Eager" wrote in message
...
On Sun, 15 Jan 2017 22:42:10 +0000, nospam wrote:

On 15/01/2017 11:20, Huge wrote:
On 2017-01-14, wrote:
On 14/01/2017 13:11, Andrew wrote:
On 13/01/2017 11:39, whisky-dave wrote:

exactly he was taking aprin so not to get a stroke as he;d heard
that it thins the blood so yuo;re less
likely to get a a blood clot

No it doesn't thin your blood. Medical myth, commonly propagated by
people who should know better (typically nurses), presumably because
they think the patient is too thick to understand how they work.

Aspirin interferes with the platelets normal function of
metamorphosing into a sticky plug when it encounters exposed
collagen, as when you cut yourself.This is measured by the bleeding
time of about 2 mins.

Warfarin, Heparin and others act on the blood coagulation stages,
normally triggered off by a cut, which pass throughseveral factors
(like Factor VIII, deficient or defective in haemophiliacs) and
eventually polymerise fibrin into strands that get enmeshed in the
platelet plug to seal the wound after the platelets have plugged it.


An interesting discussion. What's the advantage of drugs like
Clopidogrel over Warfarin or Aspirin?

Clopidogrel's benefit is primarily in those who smoke cigarettes, with
only slight benefit in those who do not.

??

Presumably it treats a particular kind of 'stickiness' mostly produced by
smoking?

No it doesnt.

It was prescribed for elderly M-I-L years ago, and she hadn't smoked for
about 30 years at the time.

It was prescribed to me quite recently and I have never smoked.

https://en.wikipedia.org/wiki/Clopidogrel says
nothing about smokers, Huge is wrong, as usual.

If the same thing had happened inside my skull, it would have been
serious. Think of the skull as a box, with brain inside and a certain
amount of space for the blood to flow through. If some of that space is
taken up by a large lump of escaped blood, there's less space for the
blood-flow, and the brain can be starved of oxygen.




Indeed it does as per 9:02 here not using an angle grinder quite but a
natty little cutter;! Enjoy:!!!


https://www.youtube.com/watch?v=3ApMJdebrFI
--
Tony Sayer