I am sure this sort of thing is well-known, but it hit me between the
eyes this morning:


"New polymer-halloysite hybrid materials--potential controlled drug
release system.

Ghebaur A, Garea SA, Iovu H.

Advanced Polymer Materials Group, University Politehnica of Bucharest,
149 Calea Victoriei, 010072 Bucharest, Romania.

Abstract

New hybrid materials based on a natural host (halloysite), biodegradable
polymer (poly(vinyl alcohol)) and diphenhydramine hydrochloride as drug
were synthesized and tested as a potential controlled drug delivery
system. The formation of these hybrid materials was proved using
different characterization methods like Spectroscopic techniques (FTIR,
XPS and UV-vis), thermogravimetrical analysis and scanning electron
microscopy (SEM). The hybrid materials exhibit different features
regarding the drug release. In vitro drug release tests showed that
there are several factors which exhibit a strong influence on the drug
release rate. Thus the initial drug concentration used at the hybrid
materials synthesis, the presence of a polymer in the hybrid composition
and the pH value of the release medium are the most important factors.

Copyright © 2012. Published by Elsevier B.V.
PMID: 22820481"

http://www.ncbi.nlm.nih.gov/pubmed/22820481

--
Rod

On 18/01/13 10:36, polygonum wrote:
I am sure this sort of thing is well-known, but it hit me between the
eyes this morning:


"New polymer-halloysite hybrid materials--potential controlled drug
release system.

Ghebaur A, Garea SA, Iovu H.

Advanced Polymer Materials Group, University Politehnica of Bucharest,
149 Calea Victoriei, 010072 Bucharest, Romania.

Abstract

New hybrid materials based on a natural host (halloysite), biodegradable
polymer (poly(vinyl alcohol)) and diphenhydramine hydrochloride as drug
were synthesized and tested as a potential controlled drug delivery
system. The formation of these hybrid materials was proved using
different characterization methods like Spectroscopic techniques (FTIR,
XPS and UV-vis), thermogravimetrical analysis and scanning electron
microscopy (SEM). The hybrid materials exhibit different features
regarding the drug release. In vitro drug release tests showed that
there are several factors which exhibit a strong influence on the drug
release rate. Thus the initial drug concentration used at the hybrid
materials synthesis, the presence of a polymer in the hybrid composition
and the pH value of the release medium are the most important factors.

Copyright © 2012. Published by Elsevier B.V.
PMID: 22820481"

http://www.ncbi.nlm.nih.gov/pubmed/22820481

Should've used an angle grinder.


--
Ineptocracy

(in-ep-toc-ra-cy) €“ a system of government where the least capable to
lead are elected by the least capable of producing, and where the
members of society least likely to sustain themselves or succeed, are
rewarded with goods and services paid for by the confiscated wealth of a
diminishing number of producers.

And what exactly does this stuff do when its bio degraded, presumably in
thehuman body?

Brian

--
Brian Gaff....Note, this account does not accept Bcc: email.
graphics are great, but the blind can't hear them
Email:
__________________________________________________ __________________________________________________ __________


"polygonum" wrote in message
...
I am sure this sort of thing is well-known, but it hit me between the
eyes this morning:


"New polymer-halloysite hybrid materials--potential controlled drug
release system.

Ghebaur A, Garea SA, Iovu H.

Advanced Polymer Materials Group, University Politehnica of Bucharest,
149 Calea Victoriei, 010072 Bucharest, Romania.

Abstract

New hybrid materials based on a natural host (halloysite), biodegradable
polymer (poly(vinyl alcohol)) and diphenhydramine hydrochloride as drug
were synthesized and tested as a potential controlled drug delivery
system. The formation of these hybrid materials was proved using
different characterization methods like Spectroscopic techniques (FTIR,
XPS and UV-vis), thermogravimetrical analysis and scanning electron
microscopy (SEM). The hybrid materials exhibit different features
regarding the drug release. In vitro drug release tests showed that
there are several factors which exhibit a strong influence on the drug
release rate. Thus the initial drug concentration used at the hybrid
materials synthesis, the presence of a polymer in the hybrid composition
and the pH value of the release medium are the most important factors.

Copyright © 2012. Published by Elsevier B.V.
PMID: 22820481"

http://www.ncbi.nlm.nih.gov/pubmed/22820481

--
Rod

On 18/01/2013 12:51, Brian Gaff wrote:
And what exactly does this stuff do when its bio degraded, presumably in
thehuman body?

Brian

An interesting question. I do not know.

--
Rod

Brian Gaff wrote:

And what exactly does this stuff do when its bio degraded, presumably in
thehuman body?

As far as I can see from the lit. it ends up as various chain length
alcohols and as ketones.

--
Burn Hollywood burn, burn down to the ground

On 18/01/13 12:51, Brian Gaff wrote:
And what exactly does this stuff do when its bio degraded, presumably in
thehuman body?

Almost nothing.

Brian



--
Ineptocracy

(in-ep-toc-ra-cy) €“ a system of government where the least capable to
lead are elected by the least capable of producing, and where the
members of society least likely to sustain themselves or succeed, are
rewarded with goods and services paid for by the confiscated wealth of a
diminishing number of producers.

On Fri, 18 Jan 2013 12:51:50 -0000, "Brian Gaff"
wrote:

And what exactly does this stuff do when its bio degraded, presumably in
thehuman body?

Makes your stools non-stick?