Edwin Pawlowski wrote:

It isn't hard to estimate the vent sizes needed to keep the bedrooms
65 F with a 70 F living room. Estimate the heat loss from the bedrooms
to the outdoors at 65 F... 880 ft^2 of R20 walls and 600 ft^2 of R40
ceiling would lose (65-30)(880/20+600/40) = 2065 Btu/h on a 30 F day.
And 2065 = 16.6Avsqrt(8')5^1.5 makes total vent area Av = 3.9 ft^2.

Once again Nick dazzles us with his math formula but fails to answer the
question.

This answers the question, and the dazzling arithmetic is 300 years old :-)

Just where and how do you run these vents and the appropriate air handler?

Put the vents in the ceiling. Forget the air handler.

And lose the sarcasm, s'il te plait.

Nick