A GFCI on a refrigerator is actually considered a human
safety threat. Not from electricity. Threat to humans is
from food poisoning. The human might not know how long or
when the electricity had tripped off.

Bedrooms now must use a different type of GFCI on all wall
receptacles. This because fires from things like extension
cords have proven to be a more serious threat. My personal
recommendation is to put an AFGI on the outlet that lights any
live Christmas tree. Others have demonstrated how a Christmas
tree fire leaves the occupants less than five minutes to get
out.

The downside to GFCIs is nuisance tripping due to electrical
appliances that have internal failures - voltage leakages.
For example, the 12 volt DC light was isolated from AC mains
by a transformer. But the chipmunks exposed one of the 12
volt wires to earth. Periodically the GFCI would trip only
because leakage across the transformer was periodically enough
to trip that GFCI. Periodic nuisance tripping because the low
voltage circuit had a problem that was safe but unacceptable.

wrote:
Are there any down sides to replace all the outlets in one's home with
GFCI's? Would refrigerators cause it to trip under normal operations?

Thanks.