Would an offset floor flange buy you enough space to sneak past that 8X8?
Offset floor flanges will typically give you a 1 1/2 inch offset between the center line of the toilet bowl horn and the drain pipe it empties into.
If not, how about this one:
Everyone makes an offset floor flange, and Sioux Chief (and I expect others) makes the angle outlet closet flange. You should be able to buy the Sioux Chief at Home Depot.