Just ran across this and wanted to share it.

From Wikipedia's article on David Byrne:
In 2008, Byrne and his production team programmed the Battery Maritime
Building, a 99-year-old ferry terminal in Manhattan, to play music.
Essentially Byrne took the old New York City building, hooked the
entire structure - pipes, heaters, pillars and all, electronically to
an old pipe organ, and made a playable musical instrument of it, for a
piece called "Playing the Building".

How cool is THAT?!

http://www.youtube.com/watch?v=Gea9SYUdJeY

R