On Jul 6, 10:34*am, LdB wrote:
I've made raised panel doors out of wood. *Standard rail and style
frame routed with a profile to hold the raised panel in place. The
raised panels are made slightly smaller that the rail and style frame
opening. Small rubber barrels are put in the slots of the frame

I'm now helping friends build their cupboards. These doors will be the
same raised panel type but are being made out of MDF.

So, do it the same as with wood. The panel shrinkage isn't
the only purpose of those rubber bits, they also keep it
from rattling.

You might use glues that can be softened/removed, and if
your friends want to spiff up the place, they can go with wood
panels on a future rebuild.