A CNC with a 4th axis rotator will make short work of things. A two pass
drill fixture with the second pass indexed off the first will do for
smaller volumes. just use a tight fitting pin inserted in one of the
pass 1 holes to align for the second pass.

Chappers wrote:
How would one go about drilling multiple 12mm & 32mm holes (26 in all!)
on different axis using a machine?

The holes have to be accurate and are on different sides of the post
itself. Obviously, manually this is very time consuming, and ideas?