?Q?OT=3a_An_antibody_that_clamps_onto_the_COVID_v irus?=?B?4oCZcyDigJhBY2hpbGxlcyBoZWVs4oCZ?=
 

Has anyone heard of this treatment?

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COVID research updates: An antibody that clamps onto the COVID viruss
€˜Achilles heel

29 January €” An antibody that clamps onto the COVID viruss €˜Achilles heel

Scientists have engineered an antibody that effectively disables
SARS-CoV-2 and closely related coronaviruses.

Laura Walker at the biopharmaceutical company Adimab in Lebanon, New
Hampshire, and her colleagues isolated antibodies from the immune cells
of a person who had recovered from a 2003 infection with the virus
SARS-CoV, which is related to SARS-CoV-2 (C. G. Rappazzo et al. Science
https://doi.org/fsbc; 2021). By tinkering with the structure of the
antibodies, the researchers created one, called ADG-2, that was
particularly effective at disabling SARS-CoV-2 in a lab dish.

The engineered antibody also disabled a variety of related
coronaviruses.When given to mice, it stopped SARS-CoV-2 from reproducing
in the rodents lungs and protected the animals from respiratory disease.

Experiments showed that ADG-2 targets receptors found on the surface of
SARS-CoV-2 and a range of similar coronaviruses. The authors dub this
receptor the Achilles heel of coronaviruses closely related to
SARS-CoV-2, and suggest that this vulnerability could be exploited to
make vaccines against emerging coronaviruses.


https://www.nature.com/articles/d41586-020-00502-w
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Maggie